High White Blood Cell Count in Dogs: Possible Causes

Neutrophils, with their high numbers, are the predominant type of white blood cells, and as such, they largely influence the increase or decrease of white blood cell counts in most cases. These cells are equipped with robust motility, phagocytic activity, and complex杀菌 abilities, enabling them to capture and eliminate pathogens in tissues, body cavities, and the bloodstream. Their ability to渗透, deform, and migrate towards infection sites, along with their phagocytic prowess, makes them crucial for the body's defense. Neutrophils make up more than 60% and no more than 77% of the total white blood cell count.

An increase in neutrophils is commonly observed in bacterial infections and acute or chronic bacterial infections, excluding acute Salmonella infections. This includes conditions such as suppurative peritonitis, gastroenteritis, pneumonia, endometritis, mastitis, and more. Major surgeries, injuries, the early stages of acidosis, and burns can also lead to an increase in neutrophils due to secondary infections.

Eosinophils and basophils, however, only constitute a small percentage of white blood cells. An increase in basophils has limited clinical significance. Eosinophilia is primarily seen in allergic diseases (such as allergic reactions), parasitic infections (like liver flukes, coccidia, and trichinosis), skin diseases (like eczema and scabies), following serum injections, and in certain malignancies.

Basophils are a type of white blood cell...

Lymphocytes account for approximately 12% to 30% of the total white blood cell count. Originating from hematopoietic stem cells in the bone marrow, they make up about a quarter of the total white blood cell count. Lymphocytes are categorized into T lymphocytes, B lymphocytes, and nonT nonB lymphocytes (such as K cells and NK cells). In conjunction with monocytes, they are responsible for the body's cellular and humoral immunity, providing specific immunity. An increase in lymphocytes is often a normal response to increased adrenaline activity, such as during exercise, stress, or postvaccination reactions. Pathological increases are more common in chronic infections and lymphomas.