Treating Hemorrhagic Enteritis in Dogs: Causes & Treatm
Canine Transmissible Enteritis, commonly known as CTE, is a prevalent disease caused by the Canine Parvovirus. This illness manifests in dogs with symptoms such as loss of appetite and vomiting, followed by the passage of yellowish or grayish diarrhea within a week. In severe cases, the diarrhea can become喷射状 and take on a foul, tomato juicelike or soy sauce smell over a period of 2 to 3 days.
As the illness progresses, the dog's overall condition rapidly worsens, sometimes leading to a state of coma and drooping of the mouth. Initially, the dog's gastrointestinal motility increases, but this ceases when blood is present in the stool. The heart rate also becomes significantly faster, often reaching 160 to 200 beats per minute, which can be indicative of CTE.
Treatment involves a combination of specific therapy and symptomatic care. Early and midstage treatment includes administering a Canine Parvovirus monoclonal antibody subcutaneously on the side of the dog's neck at a dose of 0.40 milliliters per kilogram of body weight, twice daily. This is typically done for 2 to 5 days, depending on the improvement of the dog's condition. The treatment protocol includes using CPV monoclonal antibody combined with serum on the first and second days, serum with canine leukocyte interferon on the third and fourth days, and interferon or immunoglobulin on the fifth and sixth days. Posttreatment observation and followup are crucial.
Supportive care focuses on antiemetics, hemostasis, antibacterial and antiinflammatory measures, prevention of dehydration, and correction of acidosis. Antiemetics like Emend are used to control vomiting, while hemostatic agents like Tranexamic Acid help stop bleeding. Antibacterial and antiinflammatory treatment is provided with Ampicillin powder injections. Dehydration and acidosis are addressed with oral rehydration salts, which can be administered via enema or allowed to be consumed freely. Antiviral therapy with Ribavirin is also employed, and dexamethasone is used to prevent shock in severe cases.
Enhanced care involves improving the dog's living conditions by isolating it in a dry, wellventilated, and quiet environment to minimize stress. Providing a clean drink with a mixture of salt, glucose, vitamin B complex, and vitamin C can help the dog recover. This mixture should be given for five days.
During the recovery phase, to restore gastrointestinal function and appetite, it's advisable to administer vitamin C, vitamin B, and probiotic supplements like lactobacillus tablets twice to three times a day for four days. When the dog's appetite returns, offer soft, easily digestible food, avoiding overeating or feeding difficulttodigest meals. Feeding in small, frequent meals can help prevent further gastrointestinal damage.
The Canine Parvovirus monoclonal antibody is effective in treating the disease by neutralizing the virus through inhibiting its attachment to or replication within host cells. The complement system also enhances the neutralizing effect of the monoclonal antibody. The neutralized CPV, combined with antibodies, forms antigenantibody complexes, which can stimulate the dog's active immunity, leading to recovery.
By employing symptomatic treatment, the progression of the disease can be controlled, and secondary infections prevented. Enhanced care can reduce the dog's consumption, maintain its energy levels, and boost its immune response, aiding in the dog's recovery.
